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Tirzepatide side effects are rarely dangerous when monitored, but severe, prolonged nausea can lead to dehydration or nutrient deficiency if you cannot eat adequately

For some people, this can happen at 0.5 mg or 1 mg per week

Heres what the research and my clinical experience reveal: Semaglutide is a well-established option with: Weekly injections Proven safety profile Average weight loss of 15-20% of body weight Effective appetite suppression Improvements in cardiovascular health markers Tirzepatide offers: Weekly injections Potentially greater weight loss (16-22.5% of body weight) Dual-action mechanism Similar side effect profile to semaglutide Enhanced metabolic benefits In a recent head-to-head trial , tirzepatide demonstrated superior weight loss compared to semaglutide, with participants losing an average of 20.2% versus 13.7% of their body weight at 72 weeks

More seriously, there is a risk of thyroid tumor development, including thyroid cancer