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This substantial weight loss that results from GLP-1 use can be beneficial for overall health, but often leads to specific and challenging facial aesthetic concerns such as reduced fat volume, skin laxity, and the emergence of wrinkles and a gaunt appearance

Many patients with thyroid conditions, particularly hypothyroidism, struggle with weight management, making weight-loss medications like Wegovy potentially beneficial

Your body naturally enters periods of metabolic adjustment

In anonymous complaints about Calibrate filed with the Federal Trade Commission and obtained via a Freedom of Information Act Request, one patient wrote: "I have regained half of what I originally lost, a setback representing about six months of work." Another customer said they started gaining weight back as soon as they stopped the medication cold turkey, so they got back on the medication by signing up for Calibrate's second-year program