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Conclusion Maximizing the benefits of GLP-1 therapies require a multidisciplinary approach that integrates evidence-based nutrition, physical activity, and proactive management of gastrointestinal side effects

More specifically, the ARC nucleus of the hypothalamus has been highlighted as one of the main sites mediating this action as chemical lesion of the ARC in rats ablates the anorectic action of GLP-1 (Tang-Christensen et al., 1998)

Finally, there might be consequences for how some of the neuroprotective effects of GLP1 are achieved

doi: 10.1152/physrev.00034.2006 [DOI] [PubMed] [Google Scholar] 60.Kim W, Egan JM
