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these symptoms typically peak in week 12 and improve by week 34

It's important to note that weight loss itself is an evidence-based therapy for GERD, so the weight reduction achieved with these medications may actually improve reflux symptoms in some patients, potentially offsetting any direct effects on the gastroesophageal junction

A systematic review published in Human Reproduction Update found that obesity in men is associated with reduced sperm concentration and total sperm count

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