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These findings were consistent with the network metaanalysis estimates presented in Figure 3A, and Supplement 7.1

While a calorie deficit is needed for weight loss, cutting calories and protein too much can lead to muscle loss and fatigue

AASLD 2017 Current Status of Pharmacologic Treatments for NASH No approved therapies for NASH Currently available therapeutics with (some) proven efficacy Vitamin E Pioglitazone NASH: targets for therapeutics Endpoints for clinical trials Disease Activity (steatohepatitis) = NAFLD Activity Score (NAS) Disease Progression = Fibrosis Stage Clinical outcomes : Cirrhosis (MELD, Portal hypertension), Liver-related outcome, death Adapted from Konerman MA

According to the National Survey of Childrens Health, 16.1% of children between the ages of 6 and 17 were considered obese in 2023-2024
