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Description
Jardiance is used to treat type 2 diabetes mellitus together with diet and exercise
The mechanisms include blood pressure reduction, improvement in lipid profiles, anti-inflammatory effects on the arterial wall, and possible direct cardioprotective effects through GLP-1R expressed on cardiomyocytes
Human Th17 cells express high levels of enzymatically active dipeptidylpeptidase IV (CD26) J Immunol
95 Moreover, its co-administration with RAAS inhibitors needs to be cautious to avoid the heightened risk of dehydration and volume contraction
