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Description
A comprehensive literature search was conducted across the PubMed, Embase, and Google Scholar databases for peer-reviewed articles published from inception through June 15, 2026, focusing on the landmark SURPASS, SURMOUNT, and SUMMIT trial programs, relevant cardiorenal post hoc analyses, emerging body recomposition trials, and real-world cohort-switching protocols

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GLP-1 based therapies led to statistically significant reductions in the serum levels of brain natriuretic peptide (40.16 [51.50, 28.81]
