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Semaglutide showed indirect behavioral benefits in real-world observational data

In contrast, liraglutide alone sustains weight loss but does not significantly improve measured physical fitness outcomes.
Shima Hadidchi, MD, in Apple Valley and Victorville, CA

Finally, we demonstrate that in mice, both the efficacy and tolerability of GLP1R agonists vary with the phase of the estrous cycle, being highest during proestrus (when estrogen levels peak) and lowest in diestrus (low estrogen levels)
