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Description
This results in a lower ability to promote receptor internalization compared with endogenous GLP-1, so it allows to have an increased GLP-1R expression on the cell surface, which translates in more robust insulinotropic properties, possibly explaining the enhanced insulin secretion (in both diabetic and not diabetic human islets), induced by TZP (48) ( Figure 1 )
While the terms are sometimes used interchangeably, Zepbound refers specifically to the branded prescription version of tirzepatide
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This guide covers what clinical trial data actually shows about weight regain after stopping tirzepatide, why it happens, how fast it tends to occur, and what you can do to protect your progress