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**Improvements in Health & Reduced Long-Term Costs:** * **Comorbidity Management:** Significant weight loss often leads to marked improvements or even remission of weight-related conditions like type 2 diabetes, high blood pressure, high cholesterol, sleep apnea, and knee pain

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Prescriptions and a medical evaluation are required for certain products

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Compounded tirzepatide formulations vary too much between pharmacies to support standardized studies, making it impossible to assume they'll produce the same outcomes documented in Zepbound's trials

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In addition, patients with HF can have their cardiac function and prognosis assessed using 6MWT, NT-proBNP, and QoL [51]

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