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Perhaps the time frame being considered is the issue

Ceriello A, Esposito K, Testa R, Bonfigli AR, Marra M, Giugliano D

Their A1C levels also dropped by an average of 1.3 to 1.6 percent, depending on dosage

Larger randomized controlled trials with clinical endpoints, focusing on both cardiovascular morbidity and mortality, should be performed to verify the cardioprotective properties of GLP-1R agonists in patients with CAD and select the population in whom it will be most effective
