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Mid-Stage Clinical: Treatment Duration 1216 Weeks The main players in this stage, aside from Pfizers Danuglipron (which has been discontinued), are two small-molecule GLP-1 drugs: GSBR-1290 from Suodi achieves weight loss comparable to Orforglipron at the same 12-week mark, but has significantly higher rates of adverse reactions like nausea and vomiting

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Adequate hydration becomes non-negotiable when using either tirzepatide or liraglutide, especially during the early weeks when GI side effects are most common

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