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Originally developed to treat type 2 diabetes (T2D), these drugs have since delivered major advances in managing obesity and cardiovascular risk reduction

These include nanoparticle formulations that encapsulate berberine to improve bioavailability and synthetic modifications of the molecule to increase solubility

Semaglutide, Cas no:910463-68-2 L-Histidyl-2-methylalanyl-L--glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L--aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L--glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L--glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L--glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine