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The other currently available once-weekly GLP-1 agonists in the US Astra Zenecas Bydureon (exenatide) and GSKs Tanzeum (albiglutide) require a reconstitution process that takes time to prepare before use
Every 5 kg of weight loss independently reduces systolic blood pressure by approximately 3 to 5 mmHg, reduces triglycerides, improves HDL cholesterol, reduces insulin resistance, decreases systemic inflammation, and reduces mechanical strain on the heart

Pure GLP-1 agonists such as semaglutide do not reliably move LDL
