glp-1-based treatments approved for weight loss 2025 What are GLP-1s? GLP-1 Targeted Peptide Weight Loss
Description
Thus, the growth in GLP-1 RA prescribing among patients with PCOS may reflect a combination of general expansion in GLP-1 RA use and the high prevalence of metabolic indications in this population

This imbalance is understandable, as GLP-1 RAs were originally developed for diabetes and weight management, and their effects on substance use have been discovered more recently

Clinical Trials & Approval The clinical development phase begins with Investigational New Drug (IND) submissions and proceeds through Phase I trials for safety and pharmacokinetics, Phase II for dose optimization and early efficacy, and Phase III for large-scale confirmation of therapeutic benefits
Jensen et al., 2005
