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CROHNS DISEASE (ADULT) Induction Dose Option #1 HUMIRA Pen 80 mg/0.8 mL (2) - NDC: 0074-0214-02 HUMIRA Pen 40 mg/0.4 mL (2) - NDC: 0074-0554-02 NDC: 0074-0214-02 DAY 1* 2 x 80 mg Pen (160 mg) NDC: 0074-0554-02 DAY 15 2 x 40 mg Pen (80 mg) *Administer as two 80-mg injections in 1 day or as one 80-mg injection per day for 2 consecutive days

Persistent high glucose levels have been linked to decreased testosterone levels, in part due to the downregulation of vascular endothelial growth factor (VEGF), which compromises testicular microcirculation, leading to Leydig cell dysfunction and blunted testosterone synthesis [64]

This is a preview of subscription content, access via your institution Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription 27,99 / 30 days cancel any time Subscribe to this journal Receive 12 print issues and online access 251,40 per year only 20,95 per issue Rent or buy this article Prices vary by article type from$1.95 to$39.95 Prices may be subject to local taxes which are calculated during checkout References Sanyal, A