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Description
Nausea, vomiting, constipation, bloating, gas, gastritis, and fatigue most common during initiation and dose escalation, typically improving over time
In murine models, changes in microbiota initiated by SGLT-2is were connected to diminished renal fibrosis and decreased generation of pro-inflammatory cytokines
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26 percent report that PA has led to a serious adverse event including hospitalization, permanent impairment, or death
