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Novo Nordisk is in control of GLP-1s such as: Ozempic, Wegovy, Rybelsus and Victoza

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Short- vs Long-acting GLP-1RAs and Evidence for Tachyphylaxis for Effects on Gastric Emptying GLP-1RAs have been divided into short-acting (eg, exenatide twice a day and lixisenatide) or long-acting (eg, liraglutide, dulaglutide, exenatide QW, semaglutide), based on whether their plasma concentrations return to near-zero levels between subcutaneous (SC) administrations or remain pharmacologically effective over at least 24 hours

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Mechanistically, GLP1RAs improve cardiac function by enhancing contractility and reducing myocardial injury 14,15,16 , exert vasodilatory and endothelial-protective effects, and display anti-inflammatory and anti-fibrotic actions that may limit adverse remodeling in heart failure (HF) 17

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Anyone thinking about taking them or experiencing side effects should consult with a primary care provider or another trusted health care provider to understand the risks

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