Compounded Semaglutide
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Description
This is not to suggest that all compounded GLP-1 medications are dangerous or that licensed compounding pharmacies are untrustworthy
In a randomised controlled trial with over 1800 participants comparing tirzepatide to semaglutide, the tirzepatide group reported more serious adverse events (5-7% VS 3%) and higher discontinuation rates due to adverse events (6-8.5% VS 4%)
However, in patients with T2DM (69) and, although not to the same degree, in obese patients with normal glucose tolerance (70), the overall incretin effect is reduced
Take the medication as directed by your protocols
