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Description
(2004) Chronic exposure to GLP-1R agonists promotes homologous GLP-1 receptor desensitization in vitro but does not attenuate GLP-1R-dependent glucose homeostasis in vivo

This aligns with findings published in pharmacology and biologics stability research
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Some patients benefit from combination therapy or sequential medication trials to find optimal regimens

Among female participants at the 12mg dose, 87% completed the full 48-week trial
