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A meta-analysis showed that GLP-1RA and SGLT2 inhibitor combination therapy was associated with a greater reduction in HbA1c (0.74%), body weight (1.61 kg), and systolic blood pressure (3.32 mmHg) than SGLT2 inhibitor monotherapy ( Conclusion and Perspectives GLP-1RAs are widely used in the treatment of T2D

Retatrutide is a triple receptor agonist that targets GIP, GLP-1, and glucagon receptors simultaneously
