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As tolerance develops and these symptoms resolve, some patients find their appetite returns more robustly than expected, potentially leading to increased food intake if not monitored carefully

With the ongoing obesity epidemic 1,2 and the emergence of promising new pharmacologic agents for obesity such as GLP-1 agonists, 3 providers may be increasingly called upon to consider incorporating weight-loss pharmacotherapy into clinical practice

Similarly, cholecystitis rates were approximately 0.6% with semaglutide compared to 0.2% with placebo

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications primarily used to manage type 2 diabetes mellitus and, more recently, for weight management in specific patient groups