what was the first glp 1 drug Reflections on discovery GLP-1 as a satiety hormone: Implications for obesity therapy and future directions How GLP-1 Receptor Agonists Evolved
Description
It is involved in GLP-1 secretion pathways and other intestinal hormones such as leptin, ghrelin, peptide YY, and CCK

While some patients report increased skin dryness or sensitivity to touch, temperature, or topical products during treatment, these symptoms are not definitively linked to semaglutide and may have other causes that should be evaluated by a healthcare provider

This means many have obesity

Chen Y-C, Chen T-H, Sun -C-C, et al
