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Early guidance from the American Society of Anesthesiologists recommended temporarily withholding the drugs, prompting widespread adherence across surgical specialties nationwide

Hinojosa recommends: Gradual dose increases as prescribed Slower, steady weight loss (around 1 pound per week) Regular meals with a balanced diet Avoiding extreme low-fat or very high-fat diets You dont need to avoid fat completely, but you also dont want to eat an extremely high-fat diet, he says

It is difficult to consider some confounders (such as dosage, duration of use, comorbidities, and drug combinations) that may influence the occurrence of gastrointestinal toxicity

Metformin is usually a first-line medication because the pill is easy to take and it's affordable
