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If you consume more food than your body needs, the extra sugar is converted into fat

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Studies indicate that GLP-1R activation exerts anti-inflammatory effects on macrophages, reduces endothelial dysfunction, and inhibits smooth muscle proliferation

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Tirzepatide produces more pronounced appetite suppression than semaglutide in many users, which makes the protein insufficiency risk slightly higher since appetite cues are even more blunted

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However, the functional effects of GLP-1 hormone on healthy and obese subjects in blood glucose control make T2DM a suitable target for treatment

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