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Active-treatment exposure totaled 51,346 patient-years, including 47,749 patient-years for semaglutide and 3,598 patient-years for tirzepatide

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Both GLP-1/IgG-Fc and Ex4/IgG-Fc effectively reduced fed blood glucose levels in treated mice and ameliorated diabetes symptoms, where as control IgG-Fc had no effect

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