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To minimize the risk of interactions, follow these guidelines: Provide your healthcare provider with a complete list of all medications, supplements, and alcohol use

Genetic variants in the GLP1R and GIPR genes significantly influence how your body responds to semaglutide

In particular, His7 (in the N-terminus of GLP-1) has a free alpha-amino group and an imidazole side chain that are important for the GLP-1R/GLP-1 interaction18)

To explore insured impacts further, and how this may translate to your policyholders, reach out to your local RGA representative.
