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Furthermore, in response to stress, male germ-free mice display a hyper reactive HPA axis, thus suggesting an important role of the microbiota in HPA regulation [8]
Future retatrutide studies with iohexol-measured GFR may help to inform which GFR estimation equation performs best to monitor kidney function over time during retatrutide treatment
Kidney Int 97(1):202212
Fortin SM, Roitman MF
