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The kinetics of serum miR-122 appears to be closely following the response of the translational biomarker ALT, but more work is needed to determine this

rather, by lowering the levels of glutathione-a core antioxidant molecule-it diminishes the cells capacity to counteract oxidative damage, thereby indirectly exacerbating the state of oxidative stress

This short review attempts to clarify the challenges for delivery systems designed to cross the BBB, and provides a brief description of the different types of targeted nanodelivery system that have shown potential for success in delivering drugs to the brain
