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NHPN-1010 regenerated cochlear synapses following acoustic trauma, as documented by confocal microscopy of immunolabeled cochlear sensory epithelia In examining NHPN-1010induced synaptogenesis in the IHC area, presynaptic ribbons in IHCs were counted 8 wks after either NHPN-1010 or saline intervention in the 22.6 kHz and 32 kHz regions

In pancreatic cancer, cancer-associated fibroblasts (CAFs) drive resistance to platinum through the nuclear translocation of PKM2, the upregulation of the expression of glycolysis-related genes, and the secretion of IL-8, all of which enhance DNA damage repair [59]
Adults with gout can use Krystexxa to help reduce their symptoms of gout which cannot be controlled by other treatments used to lower blood uric acid levels

risk of abnormal male genital development in male fetuses