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Still, most evidence behind BPC 157 comes from laboratory and animal research rather than large human studies

10.1016/j.bmcl.2007.05.036 146 KumarS.BalkrishnaS

While the canonical IL-4/STAT6 pathway is the well-established initiator of the M2 transcriptional program, our findings suggest that direct activation of PKA in M1 macrophages (using Db-cAMP) was sufficient to significantly enhance efferocytosis
