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doi: 10.1038/scientificamerican0809-54

Age : Beau's lines may be a typical sign of getting older as the nails lose their elasticity and become more brittle
GMP-grade workflows require scalable purification technologies such as tangential flow filtration (TFF), membrane ultrafiltration/diafiltration, chromatographic fractionation, and sterile 0.22 m filtration to ensure consistent removal of organic contaminants
