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Among the common carotenoids, AX radical cations are the most easily reduced

[12] - Kidd PM

In a study done by Suwannaroj et al [15] , it was found that SLE mice treated with NAC had a significantly lower anti-DNA antibody production at 24 weeks compared to control mice and had a modest improvement in mortality [15]

In addition to these environmental factors, other population differences, such as linkage disequilibrium of the GPx-1 locus with other specific modifying genes, the influence of other gene variants that act to modulate GPx-1 activity [such as the SelP subtypes mentioned above (252)], and/or the presence of other gene variants that act in concert with GPx-1 to modify disease risk may also explain differences among studies performed in different populations