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A three-year randomized, double-blind, placebo-controlled trial in 818 older adults (aged 50-70 years) with elevated homocysteine levels but normal serum vitamin B 12 levels found that folic acid supplementation (800 g/day) lowered homocysteine levels and improved measures of memory performance (115)

The recommended dosage varies based on individual needs, but a general range for oral supplementation is between 250 to 1,000 mg per day

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