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The application of the 5-choice serial reaction time task for the assessment of visual attentional processes and impulse control in rats
Nature 2014;509:10509
"Poor metabolizers," however, appear to totally lack the stereospecific (S)-mephenytoin hydroxylase activity, so both (S)- and (R)-mephenytoin enantiomers are N-demethylated to nirvanol, which accumulates in much higher concentrations
