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Dysregulation of DNA repair has been linked to mutations in NEK1 and FUS
2-Deoxy-D-glucose (2DG), a glycolysis inhibitor, can competitively bind to hexokinase to inhibit glycolysis, subsequently reducing the inflammatory response triggered by M1 macrophages (146) and simultaneously enhance the tolerance of macrophages to endotoxin (147)
10.1016/j.jpsychires.2010.01.015 11 AndreottiD
