glp-1 effectiveness Q&A: Long-term success of therapies hinges on more than just a prescription Relationship between exposure/dose, effectiveness and
Description
however, first-time prescribing rates declined over the same period (-6.6%)
Ethics declarations Competing interests A.B.B., F.S.W., J.D.H., D.B.W., A.D.S., M.V., Q.C., C.S., B.C., J.F., F.J.A., G.R.C., A.J., I.R
Limitations of GLP-1 in the treatment of T2D Native GLP-1 has a very short half-life (about 2 minutes) because of rapid degradation by the endogenous enzymes dipeptidyl-peptidase-IV (DPP-4)67) and neutral endopeptidase (NEP)68)
Data Availability Statement Data sharing is not applicable as no new data were generated
