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GLP-1 and dual GIP/GLP-1 medications work by slowing stomach emptying and acting on appetite centres in the brain, so you feel full sooner and stay full for longer

Similarly, the substudy of the obesity phase 2 trial showed clear promise for retatrutide in the treatment of MASLD [47], and through its GCG receptor agonism, retatrutide may offer benefits beyond WL, through weight-independent metabolic effects at the liver [40]

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Evidence That Metformin Exerts Its Anti-Diabetic Effects Through Inhibition of Complex 1 of the Mitochondrial Respiratory Chain
