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Lifestyle modifications that may help include wearing loose, soft-textured clothing made from natural fibers, using silk or satin bedsheets that produce less friction, maintaining a consistent room temperature to avoid thermal triggers, practicing stress reduction techniques since psychological stress can amplify central sensitization, and optimizing sleep hygiene since poor sleep worsens pain perception

For post-GLP-1 patients who have already achieved significant fat loss, these treatments offer limited benefit and may actually accentuate loose skin by removing underlying volume

Addressing concerns about muscle loss associated with Wegovy, Lim shared real-world data from 475 patients at SNUBH since Wegovy launched in Korea on Oct