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One real-world evidence study found that patients receiving GLP-1 receptor agonists had a higher risk of ulcerative colitis compared to those on DPP-4 inhibitors (a different diabetes drug class)

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If you want to be ready early (without taking risks), the safest approach is: stay updated on credible trial/regulatory milestones avoid unlicensed supply routes focus on sustainable foundations (protein, resistance training, sleep, side-effect management, relapse prevention) Safety warning: avoid retatrutide sold online or on social media Because retatrutide is not approved for UK use, any product sold as retatrutide outside authorised trials is a serious risk